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Interstitial Cystitis (Painful Bladder Syndrome)

Gynecology, Bladder, Interstitial Cystitis, Menopause Center Los AngelesInterstitial cystitis (IC) is a collection of chronic symptoms affecting the bladder, and is also known as painful bladder syndrome. When the kidneys filter liquid waste products from the bloodstream, the waste is called urine and is stored in the bladder. When the bladder is full, the nerves and muscles send signals to your brain, giving you the urge to urinate.

People with IC feel constant or intermittent pain and pressure in and around their bladders. They may feel the urge to urinate dozens of times per day, and experience pain and burning while urinating.

The particular symptoms can be different for each patient, and can range from mild to severe. IC is difficult to diagnose and its causes are not well-understood, which leads some experts to believe that it may actually be a group of several different diseases. Both men and women can develop IC, but the overwhelming majority of patients are female, and most patients start experiencing symptoms in their 40s.

While there is no known cure for interstitial cystitis, there are a few methods that can relieve symptoms.

Interstitial Cystitis Symptoms

Symptoms of IC are difficult to pin down. The symptoms may come and go, or they may be a constant for months or even years. In some cases, they disappear without any treatment. Some common symptoms include:

  • Pain and pressure that increase as the bladder fills with urine
  • Sharp or dull, aching pain in the pelvis, lower back, vulva, vagina, or urethra
  • Painful, stinging, or burning urination (dysuria)
  • Frequent urination (more than 8 times per day)
  • Urgent, immediate need to urinate, even after emptying the bladder
  • Painful intercourse

Another complication of IC is the possibility of bladder ulcers. IC causes inflammation in the bladder, which may lead to ulcers in some patients.

Symptoms may sometimes worsen during your period, or as a result of stress. The symptoms may also be aggravated by certain foods or drinks.

Causes of Interstitial Cystitis

Painful bladder syndrome is not very well understood, and may have several interacting causes. Experts believe a number of conditions could cause the problem:

  • Your bladder tissue is irritated or damaged by chemicals found in your urine.
  • Your body reacts to the bladder’s inflammation by releasing chemicals that cause the painful symptoms.
  • An autoimmune disorder is causing your body to attack the bladder.
  • The nerves surrounding your bladder are overly stimulated, resulting in pain during routine urinary functions.
  • Some other condition is simultaneously causing inflammation in the bladder.

How is Interstitial Cystitis Diagnosed?

Because painful bladder syndrome is so difficult to identify, your doctor will instead focus on ruling out other possible conditions, such as sexually transmitted infections, a urinary tract infection, bladder cancer, and kidney stones. Your doctor will also check for endometriosis – a gynecological condition which causes similar symptoms.

Your doctor may recommend these tests:


You provide a sample of urine in a cup.

Post-void residual urine volume

Your doctor administers an ultrasound after you urinate to measure the amount of fluid remaining in your bladder.


Your doctor takes a small sample of tissue from your urethra or bladder for testing.


Your doctor examines the inside of your urethra and bladder using a very narrow, flexible tube with a lens at the end.


Under anesthesia, your doctor can fill your bladder with a fluid or gas to get a better understanding of the problem. This can also serve a therapeutic purpose. 

Interstitial Cystitis Treatment

For about half of patients, the symptoms of painful bladder syndrome simply disappear on their own. For others, the symptoms can be a daily and nightly struggle for comfort and relief. Fortunately, there are several techniques and treatments available that may work for you. You may need to try a combination of methods, and may take a few weeks to clear up.

Talk to your doctor about these techniques:

Bladder training

If you’re urinating frequently, try to extend the interval of time between bathroom trips.

Relaxation techniques

Stress can trigger painful symptoms. Find time to relax and cut stressors from your life.


Regular exercise can help relieve symptoms, even low-intensity exercises like walking or stretching.

Loose clothing

Avoid wearing tight pants that put pressure on your bladder.

Changing eating or drinking habits

Some foods may trigger symptoms, like spicy or acidic foods, alcohol, caffeine, artificial sweeteners, sodas, and chocolate. Keep a food diary to keep track of foods that may be causing symptoms.

Quitting smoking

If lifestyle changes aren’t enough to keep your symptoms at bay, talk to your gynecologist about medical intervention options, such as:

Physical therapy

Therapeutic exercises can train your pelvic muscles to relax.


A few different drugs have been shown to be helpful in controlling painful bladder syndrome, including Pentosan, Amitriptyline, and Hydroxyzine, an antihistamine.

Pain killers

Pain medication can help manage your pain.


Injectable steroids may help with ulcers.

Dimethyl sulfoxide (DMSO)

This drug may fight inflammation, and is introduced into the bladder via catheter.


In this procedure, you are put under anesthesia and the doctor slowly fills your bladder with fluid or gas. For some patients, this can provide relief of symptoms for up to six months.

Very severe cases of painful bladder syndrome may fail to respond to any of these treatment methods. In these cases, more intensive treatments may be recommended.

Botox injections

Botox can paralyze the bladder muscles, numbing the pain. This is usually a temporary relief.


Your doctor can surgically implant small electric devices to control your nervous responses.


An immunosuppressant.


A surgeon could re-route your urine away from your bladder, bypassing the problem altogether. This procedure can be risky and is sometimes considered a last resort option.

If you have symptoms of, or suffer from Interstitial Cystitis and are in need of expert care, we invite you to establish care with us. Please click here to make an appointment or calling us at (844) 863- 6700.




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